Lactulose
- Stimulation of the growth of health-promoting bacteria in the gastrointestinal tract.
- Increases intraluminal gas formation and osmolality, thereby reducing transit time and intraluminal pH, which has a positive effect on constipation.
- Promotes the increased uptake of ammonia by colonic bacteria. The bacteria utilise the deposited ammonia in the colon as a source of nitrogen for protein synthesis. This reduces the non-ionic diffusion of ammonia from the colon into the portal vein system.
Lactulose Application
Detoxifying Effect
Hepatic Encephalopathy Treatment
High Dose
> 90 mL per day (> 60g per day)
Laxative Effect
Constipation Treatment
Medium Dose
30-60 mL per day (20-40 g per day)
Prebiotic Effect
Prebiotic
Low Dose
15 mL per day (10 g per day)
